PLD4

PLD4
Identifiers
Aliases	PLD4, C14orf175, phospholipase D family member 4
External IDs	OMIM: 618488; MGI: 2144765; HomoloGene: 16350; GeneCards: PLD4; OMA:PLD4 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	104,937,761 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	112,735,424 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; monocyte; ; C1 segment; ; bone marrow cells; ; testicle; ; spleen; ; substantia nigra; ; appendix; ; right hemisphere of cerebellum; ; hypothalamus;
	Top expressed in
	spleen; ; white matter of cerebellum; ; bone marrow; ; granulocyte; ; zone of skin; ; white adipose tissue; ; thymus; ; lung; ; jejunum; ; ileum;
	More reference expression data
	n/a
Gene ontology
Molecular function	phospholipase D activity; N-acylphosphatidylethanolamine-specific phospholipase D activity; catalytic activity; hydrolase activity; phosphatidylinositol phospholipase C activity;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; membrane; nucleus; endoplasmic reticulum; trans-Golgi network membrane; phagocytic vesicle;
Biological process	lipid catabolic process; inositol phosphate metabolic process; lipid metabolism; hematopoietic progenitor cell differentiation; phagocytosis;
	Sources:Amigo / QuickGO
Orthologs
	122618
	104759
	ENSG00000166428
	ENSMUSG00000052160
	Q96BZ4
	Q8BG07
	NM_001308174; NM_138790
	NM_178911
	NP_001295103; NP_620145
	NP_849242
	Wikidata
View/Edit Human	View/Edit Mouse

Phospholipase D family member 4 is an enzyme that in humans is encoded by the PLD4 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000166428 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000052160 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Phospholipase D family, member 4".
^ Universal protein resource accession number Q96BZ4 for "PLD4 - Phospholipase D4 - Homo sapiens" at UniProt.