PLDN

BLOC1S6
Identifiers
Aliases	BLOC1S6, BLOS6, HPS9, PA, PALLID, PLDN, biogenesis of lysosomal organelles complex 1 subunit 6
External IDs	OMIM: 604310; MGI: 1927580; HomoloGene: 40841; GeneCards: BLOC1S6; OMA:BLOC1S6 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	45,615,945 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	122,591,395 bp
RNA expression pattern
	Top expressed in
	pancreatic epithelial cell; ; epithelium of colon; ; pancreatic ductal cell; ; endothelial cell; ; germinal epithelium; ; bone marrow cells; ; pars compacta; ; superficial temporal artery; ; Brodmann area 23; ; parietal pleura;
	Top expressed in
	interventricular septum; ; otic vesicle; ; myocardium of ventricle; ; saccule; ; stroma of bone marrow; ; sternocleidomastoid muscle; ; primitive streak; ; barrel cortex; ; triceps brachii muscle; ; abdominal wall;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein homodimerization activity; actin filament binding; protein binding; identical protein binding; syntaxin binding;
Cellular component	cytoplasm; cytosol; membrane; transport vesicle; SNARE complex; extrinsic component of membrane; presynapse; axon cytoplasm; BLOC-1 complex; synapse;
Biological process	synaptic vesicle docking; positive regulation of pigment cell differentiation; melanosome organization; melanosome transport; endosome to melanosome transport; anterograde axonal transport; neuron projection development; anterograde synaptic vesicle transport;
	Sources:Amigo / QuickGO
Orthologs
	26258
	18457
	ENSG00000104164
	ENSMUSG00000005804
	Q9UL45
	Q9R0C0
	NM_001311255; NM_001311256; NM_012388
	NM_019788
	NP_001298184; NP_001298185; NP_036520
	NP_062762
	Wikidata
View/Edit Human	View/Edit Mouse

Pallidin is a protein that in humans is encoded by the PLDN gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000104164 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000005804 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Huang L, Kuo YM, Gitschier J (Dec 1999). "The pallid gene encodes a novel, syntaxin 13-interacting protein involved in platelet storage pool deficiency". Nat Genet. 23 (3): 329–32. doi:10.1038/15507. PMID 10610180. S2CID 22843205.
^ "Entrez Gene: PLDN pallidin homolog (mouse)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000104164 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000005804 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10610180-5] Huang L, Kuo YM, Gitschier J (Dec 1999). "The pallid gene encodes a novel, syntaxin 13-interacting protein involved in platelet storage pool deficiency". Nat Genet. 23 (3): 329–32. doi:10.1038/15507. PMID 10610180. S2CID 22843205.

[entrez-6] "Entrez Gene: PLDN pallidin homolog (mouse)".

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