PNPLA3

PNPLA3
Identifiers
AliasesPNPLA3, ADPN, C22orf20, iPLA(2)epsilon, patatin like phospholipase domain containing 3
External IDsOMIM: 609567; MGI: 2151796; HomoloGene: 11883; GeneCards: PNPLA3; OMA:PNPLA3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_025225

NM_054088

RefSeq (protein)

NP_079501

NP_473429
NP_001395268
NP_001395269
NP_001395270
NP_001395271

Location (UCSC)Chr 22: 43.92 – 43.96 MbChr 15: 84.05 – 84.07 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Patatin-like phospholipase domain-containing protein 3 (PNPLA3), also known as adiponutrin (ADPN), acylglycerol O-acyltransferase or calcium-independent phospholipase A2-epsilon (iPLA2-epsilon) is an enzyme that in humans is encoded by the PNPLA3 gene.[5][6][7]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000100344Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041653Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Wilson PA, Gardner SD, Lambie NM, Commans SA, Crowther DJ (September 2006). "Characterization of the human patatin-like phospholipase family". Journal of Lipid Research. 47 (9): 1940–9. doi:10.1194/jlr.M600185-JLR200. PMID 16799181.
  6. ^ Kienesberger PC, Oberer M, Lass A, Zechner R (April 2009). "Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functions". Journal of Lipid Research. 50 Suppl (Suppl): S63-8. doi:10.1194/jlr.R800082-JLR200. PMC 2674697. PMID 19029121.
  7. ^ "Entrez Gene: PNPLA3 patatin-like phospholipase domain containing 3".