POLE4

POLE4
Identifiers
Aliases	POLE4, YHHQ1, p12, polymerase (DNA) epsilon 4, accessory subunit, DNA polymerase epsilon 4, accessory subunit
External IDs	OMIM: 607269; MGI: 1914229; HomoloGene: 41339; GeneCards: POLE4; OMA:POLE4 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	74,970,128 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	82,682,346 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; cingulate gyrus; ; anterior cingulate cortex; ; mucosa of transverse colon; ; right adrenal cortex; ; popliteal artery; ; tibial arteries; ; monocyte; ; left adrenal gland; ; gastrocnemius muscle;
	Top expressed in
	zygote; ; secondary oocyte; ; primary oocyte; ; yolk sac; ; retinal pigment epithelium; ; ciliary body; ; right kidney; ; ventricular zone; ; embryo; ; iris;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; DNA binding; DNA-directed DNA polymerase activity; nucleotidyltransferase activity; protein binding; protein heterodimerization activity;
Cellular component	epsilon DNA polymerase complex; nucleus; nucleoplasm;
Biological process	histone H3 acetylation; DNA biosynthetic process; G1/S transition of mitotic cell cycle; DNA replication initiation; telomere maintenance via semi-conservative replication;
	Sources:Amigo / QuickGO
Orthologs
	56655
	66979
	ENSG00000115350
	ENSMUSG00000030042
	Q9NR33
	Q9CQ36
	NM_019896
	NM_025882; NM_001370295
	NP_063949
	NP_080158; NP_001357224
	Wikidata
View/Edit Human	View/Edit Mouse

Polymerase (DNA-directed), epsilon 4, accessory subunit is a protein that in humans is encoded by the POLE4 gene.^[5]