POU2F1

POU2F1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1CQT, 1E3O, 1GT0, 1HF0, 1O4X, 1OCT, 1POG
Identifiers
Aliases	POU2F1, OCT1, OTF1, oct-1B, POU class 2 homeobox 1, Oct1Z
External IDs	OMIM: 164175; MGI: 101898; HomoloGene: 37658; GeneCards: POU2F1; OMA:POU2F1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	167,427,345 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	165,830,247 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; secondary oocyte; ; sural nerve; ; gonad; ; testicle; ; Achilles tendon; ; cerebellar vermis; ; Skeletal muscle tissue of rectus abdominis; ; tendon of biceps brachii; ; epithelium of colon;
	Top expressed in
	Rostral migratory stream; ; zygote; ; tail of embryo; ; genital tubercle; ; secondary oocyte; ; primitive streak; ; primary oocyte; ; renal corpuscle; ; ciliary body; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	sequence-specific DNA binding; protein binding; RNA polymerase II core promoter sequence-specific DNA binding; RNA polymerase II general transcription initiation factor activity; DNA binding; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding;
Cellular component	endoplasmic reticulum; nucleus; intracellular membrane-bounded organelle; nucleoplasm; RNA polymerase II transcription regulator complex;
Biological process	negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; transcription, DNA-templated; snRNA transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; cytokine-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	5451
	18986
	ENSG00000143190
	ENSMUSG00000026565
	P14859
	P25425
	NM_001198783; NM_001198786; NM_002697; NM_001365848; NM_001365849
	NM_011137; NM_198932; NM_198933; NM_198934; NM_001368808
	NP_001185712; NP_001185715; NP_002688; NP_001352777; NP_001352778
	NP_035267; NP_945150; NP_945151; NP_945152; NP_001355737
	Wikidata
View/Edit Human	View/Edit Mouse

POU domain, class 2, transcription factor 1 is a protein that in humans is encoded by the POU2F1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000143190 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026565 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Roberts SB, Segil N, Heintz N (October 1991). "Differential phosphorylation of the transcription factor Oct1 during the cell cycle". Science. 253 (5023): 1022–6. doi:10.1126/science.1887216. PMID 1887216. S2CID 23291453.
^ "Entrez Gene: POU2F1 POU domain, class 2, transcription factor 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000143190 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000026565 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1887216-5] Roberts SB, Segil N, Heintz N (October 1991). "Differential phosphorylation of the transcription factor Oct1 during the cell cycle". Science. 253 (5023): 1022–6. doi:10.1126/science.1887216. PMID 1887216. S2CID 23291453.

[entrez-6] "Entrez Gene: POU2F1 POU domain, class 2, transcription factor 1".

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