POU3F1

POU3F1
Identifiers
Aliases	POU3F1, OCT6, OTF6, SCIP, POU class 3 homeobox 1
External IDs	OMIM: 602479; MGI: 101896; HomoloGene: 135923; GeneCards: POU3F1; OMA:POU3F1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	38,046,793 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	124,554,448 bp
RNA expression pattern
	Top expressed in
	skin of abdomen; ; tibial nerve; ; skin of leg; ; gonad; ; skin of arm; ; Region I of hippocampus proper; ; gums; ; caudate nucleus; ; sural nerve; ; putamen;
	Top expressed in
	Region I of hippocampus proper; ; barrel cortex; ; skin of external ear; ; dorsal striatum; ; ganglionic eminence; ; female urethra; ; medial ganglionic eminence; ; hair follicle; ; nucleus accumbens; ; hippocampus proper;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; transcription coactivator activity; DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	transcription regulator complex; nucleus; nucleoplasm;
Biological process	axon ensheathment; regulation of transcription by RNA polymerase II; myelination; forebrain development; Schwann cell development; brain development; regulation of transcription, DNA-templated; transcription, DNA-templated; myelination in peripheral nervous system; keratinocyte differentiation; positive regulation of transcription by RNA polymerase II; epidermis development; positive regulation of transcription, DNA-templated; positive regulation of gene expression; transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	5453
	18991
	ENSG00000185668
	ENSMUSG00000090125
	Q03052
	P21952
	NM_002699
	NM_011141
	NP_002690
	NP_035271
	Wikidata
View/Edit Human	View/Edit Mouse

POU domain, class 3, transcription factor 1 (also known as Oct-6) is a protein that in humans is encoded by the POU3F1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000185668 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000090125 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Tobler A, Schreiber E, Fontana A (Feb 1993). "The human Oct-6 POU transcription factor lacks the first 50 amino acids of its murine counterpart". Nucleic Acids Research. 21 (4): 1043. doi:10.1093/nar/21.4.1043. PMC 309249. PMID 8451175.
^ "Entrez Gene: POU3F1 POU domain, class 3, transcription factor 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000185668 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000090125 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8451175-5] Tobler A, Schreiber E, Fontana A (Feb 1993). "The human Oct-6 POU transcription factor lacks the first 50 amino acids of its murine counterpart". Nucleic Acids Research. 21 (4): 1043. doi:10.1093/nar/21.4.1043. PMC 309249. PMID 8451175.

[entrez-6] "Entrez Gene: POU3F1 POU domain, class 3, transcription factor 1".

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