POU3F2

POU3F2
Identifiers
Aliases	POU3F2, BRN2, N-Oct3, OCT7, OTF-7, OTF7, POUF3, brn-2, oct-7, POU class 3 homeobox 2
External IDs	OMIM: 600494; MGI: 101895; HomoloGene: 4095; GeneCards: POU3F2; OMA:POU3F2 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	98,839,458 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; buccal mucosa cell; ; pars reticulata; ; internal globus pallidus; ; ventral tegmental area; ; pars compacta; ; inferior ganglion of vagus nerve; ; primary visual cortex; ; superior vestibular nucleus;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; transcription coactivator activity; sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; protein binding; identical protein binding; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	transcription regulator complex; nucleus;
Biological process	cellular response to organic substance; regulation of transcription, DNA-templated; astrocyte development; hypothalamus cell differentiation; Schwann cell development; transcription by RNA polymerase II; negative regulation of gene expression; myelination in peripheral nervous system; transcription, DNA-templated; regulation of axonogenesis; forebrain ventricular zone progenitor cell division; neurohypophysis development; brain development; positive regulation of cell population proliferation; epidermis development; positive regulation of multicellular organism growth; regulation of cell differentiation; cerebral cortex radially oriented cell migration; positive regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II; nervous system development; neuron differentiation; neuron fate commitment; neuron fate specification; neuron development; cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	5454
	18992
	ENSG00000184486
	ENSMUSG00000095139
	P20265
	P31360
	NM_005604
	NM_008899
	NP_005595
	NP_032925
	Wikidata
View/Edit Human	View/Edit Mouse

POU domain, class 3, transcription factor 2 is a protein that in humans is encoded by the POU3F2 gene.^[4]^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000184486 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Schreiber E, Tobler A, Malipiero U, Schaffner W, Fontana A (January 1993). "cDNA cloning of human N-Oct3, a nervous-system specific POU domain transcription factor binding to the octamer DNA motif". Nucleic Acids Research. 21 (2): 253–8. doi:10.1093/nar/21.2.253. PMC 309100. PMID 8441633.
^ "Entrez Gene: POU3F2 POU domain, class 3, transcription factor 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000184486 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8441633-4] Schreiber E, Tobler A, Malipiero U, Schaffner W, Fontana A (January 1993). "cDNA cloning of human N-Oct3, a nervous-system specific POU domain transcription factor binding to the octamer DNA motif". Nucleic Acids Research. 21 (2): 253–8. doi:10.1093/nar/21.2.253. PMC 309100. PMID 8441633.

[entrez-5] "Entrez Gene: POU3F2 POU domain, class 3, transcription factor 2".

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