PR toxin

PR toxin
Names
	IUPAC name (11S)-8,12-Dioxo-1β,2β:7,11-diepoxy-7α-eremophil-9-en-3β-yl acetate
	Systematic IUPAC name (1aR,2R,2′R,3R,3′S,3aR,7bS)-3′-Formyl-3,3′,3a-trimethyl-6-oxo-1a,2,3a,4,6,7b-hexahydro-3H-spiro[naphtho[1,2-b]oxirene-5,2′-oxiran]-2-yl acetate
Identifiers
CAS Number	56299-00-4;
3D model (JSmol)	Interactive image;
3DMet	B01991;
ChEBI	CHEBI:7883;
ChEMBL	ChEMBL4176158;
ChemSpider	389737;
KEGG	C06079;
PubChem CID	440907;
UNII	F9W0X88AFM;
CompTox Dashboard (EPA)	DTXSID40971740 ;
	InChI InChI=1S/C17H20O6/c1-8-12(21-9(2)19)14-13(22-14)10-5-11(20)17(6-15(8,10)3)16(4,7-18)23-17/h5,7-8,12-14H,6H2,1-4H3/t8-,12+,13-,14+,15+,16+,17-/m0/s1 Key: GSPFUBNBRPVALJ-VIEAGMIOSA-N;
	SMILES C[C@H]1[C@H]([C@@H]2[C@@H](O2)C3=CC(=O)[C@@]4(C[C@]13C)[C@@](O4)(C)C=O)OC(=O)C;
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Penicillin Roquefort toxin (PR toxin) is a mycotoxin produced by the fungus Penicillium roqueforti. In 1973, PR toxin was first partially characterized by isolating moldy corn on which the fungi had grown.^[1] Although its lethal dose was determined shortly after the isolation of the chemical, details of its toxic effects were not fully clarified until 1982 in a study with mice, rats, anesthetized cats and preparations of isolated rat auricles.^[2]

^ Wei, R.D.; et al. (1973-01-25). "Isolation and Partial Characterization of a Mycotoxin from Penicillium roqueforti". American Society for Microbiology. 25 (1): 111–114. doi:10.1128/am.25.1.111-114.1973. PMC 380745. PMID 4687064.
^ Chen, F.C.; et al. (1982). "Acute toxicity of PR toxin, a mycotoxin from Penicillium roqueforti'". Toxicon. 20 (2): 433–441. doi:10.1016/0041-0101(82)90006-x. PMID 7080052.

[Wei_111–114-1] Wei, R.D.; et al. (1973-01-25). "Isolation and Partial Characterization of a Mycotoxin from Penicillium roqueforti". American Society for Microbiology. 25 (1): 111–114. doi:10.1128/am.25.1.111-114.1973. PMC 380745. PMID 4687064.

[2] Chen, F.C.; et al. (1982). "Acute toxicity of PR toxin, a mycotoxin from Penicillium roqueforti'". Toxicon. 20 (2): 433–441. doi:10.1016/0041-0101(82)90006-x. PMID 7080052.

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