26S protease regulatory subunit S10B, also known as 26S proteasome AAA-ATPase subunit Rpt4, is an enzyme that in humans is encoded by the PSMC6 gene.[5][6][7] This protein is one of the 19 essential subunits of a complete assembled 19S proteasome complex[8] Six 26S proteasome AAA-ATPase subunits (Rpt1, Rpt2, Rpt3, Rpt4 (this protein), Rpt5, and Rpt6) together with four non-ATPase subunits (Rpn1, Rpn2, Rpn10, and Rpn13) form the base sub complex of 19S regulatory particle for proteasome complex.[8]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000100519 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021832 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Fujiwara T, Watanabe TK, Tanaka K, Slaughter CA, DeMartino GN (Jun 1996). "cDNA cloning of p42, a shared subunit of two proteasome regulatory proteins, reveals a novel member of the AAA protein family". FEBS Letters. 387 (2–3): 184–8. Bibcode:1996FEBSL.387..184F. doi:10.1016/0014-5793(96)00489-9. PMID 8674546.
- ^ Tanahashi N, Suzuki M, Fujiwara T, Takahashi E, Shimbara N, Chung CH, Tanaka K (Feb 1998). "Chromosomal localization and immunological analysis of a family of human 26S proteasomal ATPases". Biochemical and Biophysical Research Communications. 243 (1): 229–32. doi:10.1006/bbrc.1997.7892. PMID 9473509.
- ^ "Entrez Gene: PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6".
- ^ a b Gu ZC, Enenkel C (Dec 2014). "Proteasome assembly". Cellular and Molecular Life Sciences. 71 (24): 4729–45. doi:10.1007/s00018-014-1699-8. PMC 11113775. PMID 25107634. S2CID 15661805.