PTPN6

PTPN6
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPTPN6, HCP, HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1, SHP-1L, SHP1, protein tyrosine phosphatase, non-receptor type 6, protein tyrosine phosphatase non-receptor type 6
External IDsOMIM: 176883; MGI: 96055; HomoloGene: 56589; GeneCards: PTPN6; OMA:PTPN6 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002831
NM_080548
NM_080549

NM_001077705
NM_013545

RefSeq (protein)

NP_002822
NP_536858
NP_536859

NP_001071173
NP_038573

Location (UCSC)Chr 12: 6.95 – 6.96 MbChr 6: 124.7 – 124.72 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Tyrosine-protein phosphatase non-receptor type 6, also known as Src homology region 2 domain-containing phosphatase-1 (SHP-1), is an enzyme that in humans is encoded by the PTPN6 gene.[5]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000111679Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000004266Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Plutzky J, Neel BG, Rosenberg RD, Eddy RL, Byers MG, Jani-Sait S, Shows TB (August 1992). "Chromosomal localization of an SH2-containing tyrosine phosphatase (PTPN6)". Genomics. 13 (3): 869–72. doi:10.1016/0888-7543(92)90172-O. PMID 1639416.