Paillamachu (died 1604), was the Mapuche toqui from 1592 to 1603 in what is now Chile.
Paillamachu replaced the slain Paillaeco, then organized and carried out the great revolt of 1598 that expelled the Spanish from Araucanía south of the Bío Bío River. He was succeeded upon his death by Huenecura in 1604.