Pancreatic polypeptide receptor 1

NPY4R
Identifiers
Aliases	NPY4R, NPY4-R, PP1, PPYR1, Y4, Pancreatic polypeptide receptor 1, neuropeptide Y receptor Y4
External IDs	OMIM: 601790; MGI: 105374; HomoloGene: 116086; GeneCards: NPY4R; OMA:NPY4R - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	46,465,958 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	33,874,446 bp
RNA expression pattern
	Top expressed in
	rectum; ; transverse colon; ; muscle layer of sigmoid colon; ; duodenum; ; mucosa of transverse colon; ; smooth muscle tissue; ; skin of abdomen; ; skin of leg; ; appendix; ; stomach;
	Top expressed in
	embryo; ; lip; ; urinary bladder; ; digastric muscle; ; stomach; ; duodenum; ; lumbar spinal ganglion; ; jejunum; ; ileum; ; submandibular gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	neuropeptide Y receptor activity; G protein-coupled receptor activity; signal transducer activity; pancreatic polypeptide receptor activity; peptide hormone binding;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane;
Biological process	signal transduction; neuropeptide signaling pathway; chemical synaptic transmission; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	5540
	19065
	ENSG00000204174
	ENSMUSG00000048337
	P0DQD5; P50391
	Q61041
	NM_001278794; NM_005972
	NM_008919
	NP_001265724; NP_001265723; NP_005963; NP_001265724
	NP_032945
	Wikidata
View/Edit Human	View/Edit Mouse

Pancreatic polypeptide receptor 1, also known as Neuropeptide Y receptor type 4, is a protein that in humans is encoded by the PPYR1 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000204174 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000048337 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lutz CM, Richards JE, Scott KL, Sinha S, Yang-Feng TL, Frankel WN, Thompson DA (December 1997). "Neuropeptide Y receptor genes mapped in human and mouse: receptors with high affinity for pancreatic polypeptide are not clustered with receptors specific for neuropeptide Y and peptide YY". Genomics. 46 (2): 287–290. doi:10.1006/geno.1997.5024. PMID 9417917.
^ "Entrez Gene: PPYR1 pancreatic polypeptide receptor 1".
^ Al-hussaniy HA, AL-Biati HA (2022-12-02). "The Role of Leptin Hormone, Neuropeptide Y, Ghrelin and Leptin/Ghrelin ratio in Obesogenesis: Leptin Hormone, Neuropeptide Y, Ghrelin and Leptin/Ghrelin ratio". Medical and Pharmaceutical Journal. 1 (2). doi:10.55940/medphar20227. ISSN 2957-6067.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000204174 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000048337 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9417917-5] Lutz CM, Richards JE, Scott KL, Sinha S, Yang-Feng TL, Frankel WN, Thompson DA (December 1997). "Neuropeptide Y receptor genes mapped in human and mouse: receptors with high affinity for pancreatic polypeptide are not clustered with receptors specific for neuropeptide Y and peptide YY". Genomics. 46 (2): 287–290. doi:10.1006/geno.1997.5024. PMID 9417917.

[entrez-6] "Entrez Gene: PPYR1 pancreatic polypeptide receptor 1".

[7] Al-hussaniy HA, AL-Biati HA (2022-12-02). "The Role of Leptin Hormone, Neuropeptide Y, Ghrelin and Leptin/Ghrelin ratio in Obesogenesis: Leptin Hormone, Neuropeptide Y, Ghrelin and Leptin/Ghrelin ratio". Medical and Pharmaceutical Journal. 1 (2). doi:10.55940/medphar20227. ISSN 2957-6067.

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