ParABS system

The parABS system is a broadly conserved molecular mechanism for plasmid partitioning and chromosome segregation in bacteria. Originally identified as a genetic element required for faithful partitioning of low-copy-number plasmids, it consists of three components: the ParA ATPase, the ParB DNA-binding protein, and the cis-acting parS sequence. The parA and parB genes are typically found in the same operon, with parS elements located within or adjacent to this operon. Collectively, these components function to ensure accurate partitioning of plasmids or whole chromosomes between bacterial daughter cells prior to cell division.^[1]

^ Surtees, JA; Funnell, BE (2003). Plasmid and chromosome traffic control: how ParA and ParB drive partition. Vol. 56. pp. 145–80. doi:10.1016/s0070-2153(03)01010-x. ISBN 9780121531560. PMID 14584729. {{cite book}}: |journal= ignored (help)

[1] Surtees, JA; Funnell, BE (2003). Plasmid and chromosome traffic control: how ParA and ParB drive partition. Vol. 56. pp. 145–80. doi:10.1016/s0070-2153(03)01010-x. ISBN 9780121531560. PMID 14584729. {{cite book}}: |journal= ignored (help)

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