Parvocellular neurosecretory cell

Not to be confused with Parvocellular cell.

Parvocellular neurosecretory cells are small neurons that produce hypothalamic releasing and inhibiting hormones. The cell bodies of these neurons are located in various nuclei of the hypothalamus or in closely related areas of the basal brain, mainly in the medial zone of the hypothalamus.[1][2] All or most of the axons of the parvocellular neurosecretory cells project to the median eminence, at the base of the brain, where their nerve terminals release the hypothalamic hormones.[1] These hormones are then immediately absorbed into the blood vessels of the hypothalamo-pituitary portal system, which carry them to the anterior pituitary gland, where they regulate the secretion of hormones into the systemic circulation.[1][3][4]

  1. ^ a b c Hall, John E. (2021). Guyton and Hall Textbook of Medical Physiology. Michael E. Hall (14th ed.). Philadelphia, PA. pp. 931–932. ISBN 978-0-323-59712-8. OCLC 1129099861.{{cite book}}: CS1 maint: location missing publisher (link)
  2. ^ Splittgerber, Ryan (2019). Snell's Clinical Neuroanatomy. Richard S. Preceded by Snell (8th ed.). Philadelphia. pp. 379–380. ISBN 978-1-4963-4675-9. OCLC 1045082168.{{cite book}}: CS1 maint: location missing publisher (link)
  3. ^ Sawchenko, PE (Dec 29, 1987). "Evidence for differential regulation of corticotropin-releasing factor and vasopressin immunoreactivities in parvocellular neurosecretory and autonomic-related projections of the paraventricular nucleus". Brain Research. 437 (2): 253–63. doi:10.1016/0006-8993(87)91641-6. PMID 3325130. S2CID 38822848.
  4. ^ Kovács, KJ; Sawchenko, PE (January 1996). "Sequence of stress-induced alterations in indices of synaptic and transcriptional activation in parvocellular neurosecretory neurons". The Journal of Neuroscience. 16 (1): 262–73. doi:10.1523/JNEUROSCI.16-01-00262.1996. PMC 6578740. PMID 8613792.