Pat Thomas, i.e. Patrick or Patricia Thomas may refer to:
- Patrick Thomas (conductor) (1932–2017), Australian orchestral conductor
- Patrick Thomas (actor) (born 1961), American
- Patrick Thomas (graphic artist) (born 1965), English
- Pat Thomas (boxer) (born 1950), Welsh
- Pat Thomas (defensive back) (born 1954), American footballer
- Pat Thomas (journalist) (born 1959), American author, journalist and campaigner
- Pat Thomas (linebacker) (born 1983), American footballer
- Pat Thomas (pianist) (born 1960), British
- Pat Thomas (American musician) (born 1964), American music journalist and musician
- Pat Thomas (Ghanaian musician), Ghanaian vocalist and songwriter
- Pat Thomas (politician) (1933–2000), North Florida politician
- Pat Thomas (singer) (died 1992), American jazz singer
- Patrick Thomas (businessman) (born 1947), French business executive
- Pat Thomas (dancer) (1922-2014)