Pearse may refer to:
- Pearse (surname), includes list of people with the name
- Pearse Island, an island on the north coast of British Columbia, Canada
- Pearse Islands, a small archipelago at the northern entrance to Johnstone Strait, near Alert Bay, British Columbia, Canada
- Pearse Museum, Dublin, Ireland
- Pearse River, Tasman, New Zealand
- Pearse Strait, Nunavut, Canada