Pefloxacin

Pefloxacin
Clinical data
ATC code	J01MA03 (WHO) ;
Pharmacokinetic data
Bioavailability	100%
Protein binding	20–30%
Metabolism	Hepatic
Elimination half-life	8.6 hours
Excretion	Mostly renal, also biliary
Identifiers
	IUPAC name 1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid;
CAS Number	70458-92-3 ;
PubChem CID	51081;
DrugBank	DB00487 ;
ChemSpider	46291 ;
UNII	2H52Z9F2Q5;
KEGG	D02306 ;
ChEBI	CHEBI:50199 ;
ChEMBL	ChEMBL267648 ;
CompTox Dashboard (EPA)	DTXSID3048493 ;
ECHA InfoCard	100.067.807
Chemical and physical data
Formula	C17H20FN3O3
Molar mass	333.363 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(O)\C2=C\N(c1cc(c(F)cc1C2=O)N3CCN(C)CC3)CC;
	InChI InChI=1S/C17H20FN3O3/c1-3-20-10-12(17(23)24)16(22)11-8-13(18)15(9-14(11)20)21-6-4-19(2)5-7-21/h8-10H,3-7H2,1-2H3,(H,23,24) ; Key:FHFYDNQZQSQIAI-UHFFFAOYSA-N ;
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Pefloxacin is a quinolone antibiotic used to treat bacterial infections. Pefloxacin has not been approved for use in the United States.

Clinical data

ATC code	J01MA03 (WHO)
Pharmacokinetic data
Bioavailability	100%
Protein binding	20–30%
Metabolism	Hepatic
Elimination half-life	8.6 hours
Excretion	Mostly renal, also biliary
Identifiers
IUPAC name 1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid
CAS Number	70458-92-3^Y
PubChem CID	51081
DrugBank	DB00487^Y
ChemSpider	46291^Y
UNII	2H52Z9F2Q5
KEGG	D02306^Y
ChEBI	CHEBI:50199^Y
ChEMBL	ChEMBL267648^Y
CompTox Dashboard (EPA)	DTXSID3048493
ECHA InfoCard	100.067.807
Chemical and physical data
Formula	C₁₇H₂₀FN₃O₃
Molar mass	333.363 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(O)\C2=C\N(c1cc(c(F)cc1C2=O)N3CCN(C)CC3)CC
InChI InChI=1S/C17H20FN3O3/c1-3-20-10-12(17(23)24)16(22)11-8-13(18)15(9-14(11)20)21-6-4-19(2)5-7-21/h8-10H,3-7H2,1-2H3,(H,23,24)^Y Key:FHFYDNQZQSQIAI-UHFFFAOYSA-N^Y
(verify)