Periplasm

The periplasm is a concentrated gel-like matrix in the space between the inner cytoplasmic membrane and the bacterial outer membrane called the periplasmic space in Gram-negative (more accurately "diderm") bacteria. Using cryo-electron microscopy it has been found that a much smaller periplasmic space is also present in Gram-positive bacteria (more accurately "monoderm"), between cell wall and the plasma membrane.[1][2] The periplasm may constitute up to 40% of the total cell volume of gram-negative bacteria, but is a much smaller percentage in gram-positive bacteria.[3]

  1. ^ Matias VR, Beveridge TJ (April 2005). "Cryo-electron microscopy reveals native polymeric cell wall structure in Bacillus subtilis 168 and the existence of a periplasmic space". Molecular Microbiology. 56 (1): 240–251. doi:10.1111/j.1365-2958.2005.04535.x. PMID 15773993. S2CID 11013569.
  2. ^ Zuber B, Haenni M, Ribeiro T, Minnig K, Lopes F, Moreillon P, Dubochet J (September 2006). "Granular layer in the periplasmic space of gram-positive bacteria and fine structures of Enterococcus gallinarum and Streptococcus gordonii septa revealed by cryo-electron microscopy of vitreous sections". Journal of Bacteriology. 188 (18): 6652–6660. doi:10.1128/JB.00391-06. PMC 1595480. PMID 16952957.
  3. ^ Holst O, Seltmann G (January 2002). The Bacterial Cell Wall. Berlin: Springer. ISBN 3-540-42608-6.