Clinical data | |
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Trade names | Veetids, Apocillin,[1] others |
Other names | penicillin phenoxymethyl, penicillin V, penicillin VK |
AHFS/Drugs.com | Monograph |
MedlinePlus | a685015 |
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Routes of administration | By mouth |
ATC code | |
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Pharmacokinetic data | |
Bioavailability | 60% |
Protein binding | 80% |
Metabolism | Liver |
Elimination half-life | 30–60 min |
Excretion | Kidney |
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PubChem CID | |
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KEGG | |
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CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.001.566 |
Chemical and physical data | |
Formula | C16H18N2O5S |
Molar mass | 350.39 g·mol−1 |
3D model (JSmol) | |
Melting point | 120–128 °C (248–262 °F) |
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Phenoxymethylpenicillin, also known as penicillin V (PcV) and penicillin VK, is an antibiotic useful for the treatment of a number of bacterial infections.[2] Specifically it is used for the treatment of strep throat, otitis media, and cellulitis.[2] It is also used to prevent rheumatic fever and to prevent infections following removal of the spleen.[2] It is given by mouth.[2]
Side effects include diarrhea, nausea, and allergic reactions including anaphylaxis.[2] It is not recommended in those with a history of penicillin allergy.[2] It is relatively safe for use during pregnancy.[3] It is in the penicillin and beta lactam family of medications.[4] It usually results in bacterial death.[4]
Phenoxymethylpenicillin was first made in 1948 by Eli Lilly.[5]: 121 It is on the World Health Organization's List of Essential Medicines.[6] It is available as a generic medication.[4] In 2021, it was the 256th most commonly prescribed medication in the United States, with more than 1 million prescriptions.[7][8]
fenoksymetylpenicillin