Phosphatidylcholine transfer protein

PCTP
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPCTP, Pctp, PC-TP, StarD2, phosphatidylcholine transfer protein
External IDsOMIM: 606055; MGI: 107375; HomoloGene: 32054; GeneCards: PCTP; OMA:PCTP - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001102402
NM_021213
NM_001330377
NM_001330378

NM_008796
NM_001316372

RefSeq (protein)

NP_001095872
NP_001317306
NP_001317307
NP_067036

NP_001303301
NP_032822

Location (UCSC)Chr 17: 55.75 – 55.84 MbChr 11: 89.87 – 89.89 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Phosphatidylcholine transfer protein (PCTP), also known as StAR-related lipid transfer domain protein 2 (STARD2), is a specific intracellular phospholipid binding protein that can transfer phosphatidylcholine between different membranes in the cytosol.[5][6]

In humans, phosphatidylcholine transfer protein is encoded by the PCTP gene.[7][8]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000141179Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020553Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ van Golde LM, Oldenborg V, Post M, Batenburg JJ, Poorthuis BJ, Wirtz KW (July 1980). "Phospholipid transfer proteins in rat lung. Identification of a protein specific for phosphatidylglycerol". J. Biol. Chem. 255 (13): 6011–3. doi:10.1016/S0021-9258(18)43688-5. PMID 7391000.
  6. ^ Wirtz KW (July 1991). "Phospholipid transfer proteins". Annu. Rev. Biochem. 60 (13): 73–99. doi:10.1146/annurev.bi.60.070191.000445. PMID 1883207.
  7. ^ "Entrez Gene: phosphatidylcholine transfer protein".
  8. ^ van Helvoort A, de Brouwer A, Ottenhoff R, Brouwers JF, Wijnholds J, Beijnen JH, Rijneveld A, van der Poll T, van der Valk MA, Majoor D, Voorhout W, Wirtz KW, Elferink RP, Borst P (September 1999). "Mice without phosphatidylcholine transfer protein have no defects in the secretion of phosphatidylcholine into bile or into lung airspaces". Proc. Natl. Acad. Sci. U.S.A. 96 (20): 11501–6. Bibcode:1999PNAS...9611501V. doi:10.1073/pnas.96.20.11501. PMC 18063. PMID 10500206.