Plantar fibromatosis

Plantar fibromatosis
Other names	Ledderhose's disease
This condition is inherited in an autosomal dominant manner[1]
Specialty	Rheumatology

Plantar fascial fibromatosis, also known as Ledderhose's disease, Morbus Ledderhose, and plantar fibromatosis, is a relatively uncommon^[2] non-malignant thickening of the feet's deep connective tissue, or fascia. In the beginning, where nodules start growing in the fascia of the foot, the disease is minor.^{[citation needed]} Over time, walking becomes painful. The disease is named after Georg Ledderhose, a German surgeon who described the condition for the first time in 1894.^[3][4] A similar disease is Dupuytren's disease, which affects the hand and causes bent hand or fingers.

As in most forms of fibromatosis, it is usually benign and its onset varies with each patient.^[5] The nodules are typically slow growing^[2][5] and most often found in the central and medial portions of the plantar fascia.^[2] Occasionally, the nodules may lie dormant for months to years only to begin rapid and unexpected growth.^[5] Options for intervention include radiation therapy, cryosurgery, treatment with collagenase clostridium histolyticum, or surgical removal only if discomfort hinders walking.^[6]