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| Names | |
|---|---|
| IUPAC name
Poly[oxy(1-oxo-1,2-ethanediyl)]
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| Identifiers | |
3D model (JSmol)
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| ChemSpider |
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| ECHA InfoCard | 100.249.865 |
| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| (C2H2O2)n | |
| Molar mass | (58.04)n |
| Density | 1.530 g/cm3 at 25 °C |
| Melting point | 225 to 230 °C (437 to 446 °F; 498 to 503 K) |
| Boiling point | Decomposes |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Polyglycolide or poly(glycolic acid) (PGA), also spelled as polyglycolic acid, is a biodegradable, thermoplastic polymer and the simplest linear, aliphatic polyester. It can be prepared starting from glycolic acid by means of polycondensation or ring-opening polymerization. PGA has been known since 1954 as a tough fiber-forming polymer. Owing to its hydrolytic instability, however, its use has initially been limited.[1] Currently polyglycolide and its copolymers (poly(lactic-co-glycolic acid) with lactic acid, poly(glycolide-co-caprolactone) with ε-caprolactone and poly (glycolide-co-trimethylene carbonate) with trimethylene carbonate) are widely used as a material for the synthesis of absorbable sutures and are being evaluated in the biomedical field.[2]
- ^ Gilding, D. K.; A. M. Reed (December 1979). "Biodegradable polymers for use in surgery - polyglycolic/poly (lactic acid) homo- and copolymers: 1". Polymer. 20 (12): 1459–1464. doi:10.1016/0032-3861(79)90009-0.
- ^ Middleton, J.; A. Tipton (March 1998). "Synthetic biodegradable polymers as medical devices". Medical Plastics and Biomaterials Magazine. Archived from the original on 2007-03-12. Retrieved 2006-07-04.