Big Butte Creek is a 12-mile (19 km) long tributary of the Rogue River located in the U.S. state of Oregon. It drains approximately 245 square miles (630 km2) of Jackson County. The north fork of the creek begins on Rustler Peak and the south fork's headwaters are near Mount McLoughlin. They meet near Butte Falls, and Big Butte Creek flows generally northwest until it empties into the Rogue River about 1 mile (1.6 km) southwest of Lost Creek Dam. Big Butte Creek's watershed was originally settled over 8,000 years ago by Native Americans. In the Rogue River Wars of the 1850s, most of the Native Americans were either killed or forced onto Indian reservations. The first European American settlers arrived in the 1860s, and the area was quickly developed. The creek was named after Snowy Butte, an early name for Mount McLoughlin. In the late 19th century, the watershed was primarily used for agriculture and logging. Big Butte Springs, located in the watershed, provides clean drinking water to over 115,000 residents of the Rogue Valley. It emits over 26,000,000 US gallons (98,000,000 L) of water per day. Water from Big Butte Creek also is diverted for irrigation in several other places. The water quality of the Big Butte Creek watershed is generally high, and supports several species of trout and salmon. The watershed is also home to over 152 species of birds, 63 species of mammals, 19 species of reptiles, and numerous plants. The Poverty Flats region was designated an Area of Critical Environmental Concern by the Bureau of Land Management in 1995 to protect several rare species of plants.