Pospiviroid RY motif stem loop

Pospiviroid RY motif stem loop
Pospiviroid RY motif stem loop
	Predicted secondary structure and sequence conservation of Pospi_RY
Identifiers
Symbol	Pospi_RY
Rfam	RF00362
Other data
RNA type	Cis-reg
Domain(s)	Viroids
SO	SO:0000233
PDB structures	PDBe

The Pospiviroid RY motif stem loop is an RNA element found in Pospiviroids such as potato spindle tuber viroid (PSTVd). The RY nucleotide sequence motif (5'-ACAGG and CUCUUCC-5') in PSTVd, is thought to bind with the tomato protein Virp1. The exact function of this motif and the significance of Virp1 binding is unknown. It is however thought that RY motifs are essential for establishing a viroid infection.^[1]

^ Gozmanova M, Denti MA, Minkov IN, Tsagris M, Tabler M (October 2003). "Characterization of the RNA motif responsible for the specific interaction of potato spindle tuber viroid RNA (PSTVd) and the tomato protein Virp1". Nucleic Acids Research. 31 (19): 5534–5543. doi:10.1093/nar/gkg777. PMC 206474. PMID 14500815.

[1] Gozmanova M, Denti MA, Minkov IN, Tsagris M, Tabler M (October 2003). "Characterization of the RNA motif responsible for the specific interaction of potato spindle tuber viroid RNA (PSTVd) and the tomato protein Virp1". Nucleic Acids Research. 31 (19): 5534–5543. doi:10.1093/nar/gkg777. PMC 206474. PMID 14500815.

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