Posterior polymorphous corneal dystrophy

Posterior polymorphous corneal dystrophy
Posterior polymorphous corneal dystrophy
Other names	Ophthalmology
	Appearance of the abnormal corneal endothelial cells that have become transformed into stratified squamous epithelium. Periodic acid Schiff (PAS) stain

Posterior polymorphous corneal dystrophy (PPCD; sometimes also Schlichting dystrophy) is a type of corneal dystrophy, characterised by changes in Descemet's membrane and endothelial layer. Symptoms mainly consist of decreased vision due to corneal edema. In some cases they are present from birth, other patients are asymptomatic. Histopathological analysis shows that the cells of endothelium have some characteristics of epithelial cells and have become multilayered. The disease was first described in 1916 by Koeppe as keratitis bullosa interna.^[1]

^ Albrecht von Graefes (1916). "Klinische Beobachtungen mit der Nernstspaltlampe und dem Hornhautmikroskop". Arch. Klin. Exp. Ophthal. 91 (3): 363–379. doi:10.1007/BF01974655.

[Koeppe1916-1] Albrecht von Graefes (1916). "Klinische Beobachtungen mit der Nernstspaltlampe und dem Hornhautmikroskop". Arch. Klin. Exp. Ophthal. 91 (3): 363–379. doi:10.1007/BF01974655.

[1]