Precision cut lung slices or PCLS refer to thin sections of lung tissue that are prepared with high precision and are typically used for experimental purposes in the field of respiratory research.[1] These slices are utilized to study various aspects of lung physiology, pathology, and pharmacology, providing researchers with a valuable tool for investigating lung diseases and testing the effects of drugs on lung tissue.[2]
Precision cut lung slices are prepared using specialized equipment called Vibratomes, ensuring that the tissue remains viable and retains its structural and functional characteristics, making them ideal for a wide range of experimental applications.[3][4]