Prest is a surname. Notable people with the surname include:
- Agnes Prest, English Protestant martyr
- Arthur Prest, Nigerian politician
- Bill Prest, Australian politician
- Cedar Prest, Australian artist
- Charles Prest, English cricketer
- Edward Prest, English cricketer
- Edward Prest (priest), British archdeacon
- Harold Prest, English cricketer
- John Prest, British historian
- Martín Prest, Argentine footballer
- Sid Prest, Canadian politician
- Steve Prest, English snooker player
- Thomas Peckett Prest, British writer
- Tommy Prest, English footballer
- Warren Prest, Australian rules footballer
- Wilfrid Prest, Australian academic
- William Prest, English cricketer and footballer
- William Prest (Cambridgeshire cricketer), English cricketer