Prokineticin receptor 2

PROKR2
Identifiers
Aliases	PROKR2, GPR73L1, GPR73b, GPRg2, HH3, KAL3, PKR2, dJ680N4.3, prokineticin receptor 2
External IDs	OMIM: 607123; MGI: 2181363; HomoloGene: 16368; GeneCards: PROKR2; OMA:PROKR2 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	5,316,954 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	132,227,367 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; prefrontal cortex; ; Brodmann area 9; ; anterior cingulate cortex; ; lymph node; ; right frontal lobe; ; bone marrow; ; hippocampus proper; ; superior frontal gyrus;
	Top expressed in
	Rostral migratory stream; ; lumbar spinal ganglion; ; suprachiasmatic nucleus; ; tail of embryo; ; medial ganglionic eminence; ; olfactory bulb; ; Gonadal ridge; ; thymus; ; Sertoli cell; ; anterior amygdaloid area;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	signal transducer activity; neuropeptide Y receptor activity; pancreatic polypeptide receptor activity; G protein-coupled receptor activity;
Cellular component	membrane; integral component of membrane; plasma membrane; integral component of plasma membrane;
Biological process	circadian rhythm; signal transduction; neuropeptide signaling pathway; chemical synaptic transmission; feeding behavior; blood circulation; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	128674
	246313
	ENSG00000101292
	ENSMUSG00000050558
	Q8NFJ6
	Q8K458
	NM_144773
	NM_144944
	NP_658986
	NP_659193
	Wikidata
View/Edit Human	View/Edit Mouse

Prokineticin receptor 2 (PKR₂), is a dimeric^[5] G protein-coupled receptor encoded by the PROKR2 gene in humans.^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000101292 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000050558 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Sposini S, Caltabiano G, Hanyaloglu AC, Miele R (January 2015). "Identification of transmembrane domains that regulate spatial arrangements and activity of prokineticin receptor 2 dimers". Molecular and Cellular Endocrinology. 399: 362–372. doi:10.1016/j.mce.2014.10.024. hdl:10044/1/31246. PMID 25449422. S2CID 13491537.
^ Cite error: The named reference entrez was invoked but never defined (see the help page).

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000101292 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000050558 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[:0-5] Sposini S, Caltabiano G, Hanyaloglu AC, Miele R (January 2015). "Identification of transmembrane domains that regulate spatial arrangements and activity of prokineticin receptor 2 dimers". Molecular and Cellular Endocrinology. 399: 362–372. doi:10.1016/j.mce.2014.10.024. hdl:10044/1/31246. PMID 25449422. S2CID 13491537.

[entrez-6] Cite error: The named reference entrez was invoked but never defined (see the help page).

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