Prometheus Bound is an 1847 oil painting by American artist Thomas Cole. Prometheus Bound is one of Cole's largest paintings, and like his other major works of the 1840s it was not the result of a commission. It draws from the ancient Greek tragedy Prometheus Bound by Aeschylus. In the painting, Prometheus is chained to a rock on Mount Caucasus in Scythia. Zeus has punished him for endowing humans with life, knowledge, and specifically for giving humans fire. Each day a raptor comes to feed on Prometheus's liver, which regrows between visits, making Zeus's punishment even more cruel.
The allegorical painting is among Cole's last works, but Cole never commented on the theme of the work. Art historians have tentatively linked the bondage of Prometheus to abolitionist sentiment by reviewing the presentation of the mythical figure in contemporaneous literature. Cole sent it to London for an 1847 exhibit and competition to decorate the Houses of Parliament, and the painting was still in London when he died. It thus received little exhibition in the United States in the 1840s, making its reception (and its theme) difficult to judge.