Prophylactic salpingectomy

Female reproductive system

Prophylactic salpingectomy is a preventative surgical technique performed on patients who are at higher risk of having ovarian cancer, such as individuals who may have pathogenic variants of the BRCA1 or BRCA2 gene.[1] Originally salpingectomy was used in cases of ectopic pregnancies.[2] As a preventative surgery, however, it involves the removal of the fallopian tubes. By not removing the ovaries this procedure is advantageous to individuals who are still of child bearing age. It also reduces risks such as cardiovascular disease and osteoporosis which are associated with the removal of the ovaries.[1]

  1. ^ a b Kwon, Janice S.; Tinker, Anna; Pansegrau, Gary; McAlpine, Jessica; Housty, Melissa; McCullum, Mary; Gilks, C. Blake (January 2013). "Prophylactic Salpingectomy and Delayed Oophorectomy as an Alternative for BRCA Mutation Carriers". Obstetrics & Gynecology. 121 (1): 14–24. doi:10.1097/aog.0b013e3182783c2f. PMID 23232752. S2CID 41081248.
  2. ^ Strandell, A.; Lindhard, A.; Waldenström, U.; Thorburn, J. (2001-06-01). "Prophylactic salpingectomy does not impair the ovarian response in IVF treatment". Human Reproduction (Oxford, England). 16 (6): 1135–1139. doi:10.1093/humrep/16.6.1135. ISSN 0268-1161. PMID 11387282.