Combination of | |
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Pseudoephedrine | Sympathomimetic |
Loratadine | H1 antagonist |
Clinical data | |
Trade names | Claritin-D, others |
AHFS/Drugs.com | claritin-d |
Routes of administration | By mouth |
ATC code | |
Legal status | |
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Identifiers | |
CAS Number | |
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Pseudoephedrine/loratadine, sold under the brand name Claritin-D among others, is an orally administered combination drug used for the treatment of allergic rhinitis (hay fever) and the common cold.[1] Pseudoephedrine, one of the naturally occurring alkaloids of ephedra, is a sympathomimetic used as a decongestant.[medical citation needed] It produces a decongestant effect that is facilitated by the vasoconstriction in the mucosal capillaries of the upper respiratory areas.[medical citation needed] Loratadine is a long-acting antihistamine (H1 histamine antagonist) that is less sedating than older substances of its type.[medical citation needed]