RAD51C

RAD51C
Identifiers
Aliases	RAD51C, BROVCA3, FANCO, R51H3, RAD51L2, RAD51 paralog C
External IDs	OMIM: 602774; MGI: 2150020; HomoloGene: 14238; GeneCards: RAD51C; OMA:RAD51C - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	58,735,611 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	87,295,780 bp
RNA expression pattern
	Top expressed in
	gonad; ; right testis; ; left testis; ; testicle; ; right frontal lobe; ; ventricular zone; ; Brodmann area 9; ; oocyte; ; prefrontal cortex; ; right auricle;
	Top expressed in
	secondary oocyte; ; zygote; ; primary oocyte; ; seminiferous tubule; ; endocardial cushion; ; spermatocyte; ; ventricular zone; ; neural layer of retina; ; tail of embryo; ; atrioventricular valve;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	crossover junction endodeoxyribonuclease activity; DNA binding; nucleotide binding; ATP-dependent activity, acting on DNA; DNA strand exchange activity; single-stranded DNA binding; protein binding; four-way junction DNA binding; double-stranded DNA binding; ATP binding;
Cellular component	cytoplasm; replication fork; Rad51C-XRCC3 complex; mitochondrion; perinuclear region of cytoplasm; Rad51B-Rad51C-Rad51D-XRCC2 complex; Holliday junction resolvase complex; nucleus; cytosol; cell junction; intracellular membrane-bounded organelle; nucleoplasm;
Biological process	strand invasion; response to ionizing radiation; reciprocal meiotic recombination; DNA recombination; male meiosis I; blood coagulation; female meiosis sister chromatid cohesion; sister chromatid cohesion; cellular response to DNA damage stimulus; telomere maintenance via recombination; spermatogenesis; positive regulation of G2/M transition of mitotic cell cycle; mitotic recombination; DNA repair; double-strand break repair via homologous recombination; meiotic DNA recombinase assembly;
	Sources:Amigo / QuickGO
Orthologs
	5889
	114714
	ENSG00000108384
	ENSMUSG00000007646
	O43502
	Q924H5
	NM_002876; NM_058216
	NM_001291440; NM_053269
	NP_002867; NP_478123
	NP_001278369; NP_444499
	Wikidata
View/Edit Human	View/Edit Mouse

RAD51 homolog C (S. cerevisiae), also known as RAD51C, is a protein which in humans is encoded by the RAD51C gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000108384 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000007646 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Cite error: The named reference entrez was invoked but never defined (see the help page).
^ Dosanjh MK, Collins DW, Fan W, Lennon GG, Albala JS, Shen Z, Schild D (March 1998). "Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes". Nucleic Acids Research. 26 (5): 1179–84. doi:10.1093/nar/26.5.1179. PMC 147393. PMID 9469824.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000108384 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000007646 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] Cite error: The named reference entrez was invoked but never defined (see the help page).

[pmid9469824-6] Dosanjh MK, Collins DW, Fan W, Lennon GG, Albala JS, Shen Z, Schild D (March 1998). "Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes". Nucleic Acids Research. 26 (5): 1179–84. doi:10.1093/nar/26.5.1179. PMC 147393. PMID 9469824.

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