RELB

RELB
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1ZK9, 1ZKA, 2V2T, 3DO7, 3JSS, 3JUZ, 3JV0, 3JV4, 3JV6, 4JGM, 4JHB
Identifiers
Aliases	RELB, I-REL, IREL, REL-B, RELB proto-oncogene, NF-kB subunit, IMD53
External IDs	OMIM: 604758; MGI: 103289; HomoloGene: 4747; GeneCards: RELB; OMA:RELB - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	45,038,198 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	19,363,363 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; mucosa of transverse colon; ; cartilage tissue; ; monocyte; ; spleen; ; olfactory zone of nasal mucosa; ; blood; ; upper lobe of left lung; ; stromal cell of endometrium; ; muscle of thigh;
	Top expressed in
	mesenteric lymph nodes; ; jejunum; ; intestinal villus; ; granulocyte; ; spleen; ; duodenum; ; lactiferous gland; ; colon; ; left colon; ; thymus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; transcription corepressor activity; DNA-binding transcription factor activity; chromatin binding; protein binding; protein kinase binding; identical protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding;
Cellular component	I-kappaB/NF-kappaB complex; nucleoplasm; microtubule organizing center; cytoskeleton; nucleus; cytoplasm; cytosol; centrosome; protein-containing complex; transcription repressor complex;
Biological process	response to cytokine; antigen processing and presentation; regulation of transcription, DNA-templated; rhythmic process; regulation of transcription by RNA polymerase II; myeloid dendritic cell differentiation; stimulatory C-type lectin receptor signaling pathway; negative regulation of transcription by RNA polymerase II; T-helper 1 cell differentiation; negative regulation of interferon-beta production; circadian regulation of gene expression; transcription, DNA-templated; cellular response to osmotic stress; positive regulation of gene expression; NIK/NF-kappaB signaling; T-helper 1 type immune response; inflammatory response; negative regulation of transcription, DNA-templated; I-kappaB kinase/NF-kappaB signaling; positive regulation of transcription by RNA polymerase II; innate immune response; lymphocyte differentiation;
	Sources:Amigo / QuickGO
Orthologs
	5971
	19698
	ENSG00000104856
	ENSMUSG00000002983
	Q01201
	Q04863
	NM_006509
	NM_001290457; NM_009046
	NP_006500
	NP_001277386; NP_033072
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor RelB is a protein that in humans is encoded by the RELB gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000104856 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000002983 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Bours V, Burd PR, Brown K, Villalobos J, Park S, Ryseck RP, et al. (February 1992). "A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site". Molecular and Cellular Biology. 12 (2): 685–95. doi:10.1128/MCB.12.2.685. PMC 364259. PMID 1531086.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000104856 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000002983 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1531086-5] Bours V, Burd PR, Brown K, Villalobos J, Park S, Ryseck RP, et al. (February 1992). "A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site". Molecular and Cellular Biology. 12 (2): 685–95. doi:10.1128/MCB.12.2.685. PMC 364259. PMID 1531086.

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