RFC3

RFC3
Identifiers
Aliases	RFC3, RFC38, replication factor C subunit 3
External IDs	OMIM: 600405; MGI: 1916513; HomoloGene: 2188; GeneCards: RFC3; OMA:RFC3 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	33,966,558 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	151,574,707 bp
RNA expression pattern
	Top expressed in
	gonad; ; ventricular zone; ; embryo; ; ganglionic eminence; ; secondary oocyte; ; testicle; ; right adrenal cortex; ; left adrenal gland; ; left adrenal cortex; ; appendix;
	Top expressed in
	medial ganglionic eminence; ; abdominal wall; ; maxillary prominence; ; mandibular prominence; ; embryo; ; embryo; ; epiblast; ; ventricular zone; ; otic placode; ; endocardial cushion;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	single-stranded DNA helicase activity; ATPase activity; protein binding; DNA binding; DNA clamp loader activity;
Cellular component	Ctf18 RFC-like complex; nucleoplasm; DNA replication factor C complex; nucleus;
Biological process	nucleotide-excision repair, DNA gap filling; DNA synthesis involved in DNA repair; error-free translesion synthesis; DNA strand elongation involved in DNA replication; error-prone translesion synthesis; positive regulation of DNA-directed DNA polymerase activity; response to organophosphorus; translesion synthesis; transcription-coupled nucleotide-excision repair; nucleotide-excision repair, DNA incision; DNA replication; nucleotide-excision repair, DNA incision, 5'-to lesion; telomere maintenance via semi-conservative replication; DNA-dependent DNA replication; regulation of signal transduction by p53 class mediator;
	Sources:Amigo / QuickGO
Orthologs
	5983
	69263
	ENSG00000133119
	ENSMUSG00000033970
	P40938
	Q8R323
	NM_002915; NM_181558
	NM_027009
	NP_002906; NP_853536
	NP_081285
	Wikidata
View/Edit Human	View/Edit Mouse

Replication factor C subunit 3 is a protein that in humans is encoded by the RFC3 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000133119 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000033970 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Okumura K, Nogami M, Taguchi H, Dean FB, Chen M, Pan ZQ, Hurwitz J, Shiratori A, Murakami Y, Ozawa K (Jan 1995). "Assignment of the 36.5-kDa (RFC5), 37-kDa (RFC4), 38-kDa (RFC3), and 40-kDa (RFC2) subunit genes of human replication factor C to chromosome bands 12q24.2-q24.3, 3q27, 13q12.3-q13, and 7q11.23". Genomics. 25 (1): 274–8. doi:10.1016/0888-7543(95)80135-9. PMID 7774928.
^ "Entrez Gene: RFC3 replication factor C (activator 1) 3, 38kDa".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000133119 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000033970 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7774928-5] Okumura K, Nogami M, Taguchi H, Dean FB, Chen M, Pan ZQ, Hurwitz J, Shiratori A, Murakami Y, Ozawa K (Jan 1995). "Assignment of the 36.5-kDa (RFC5), 37-kDa (RFC4), 38-kDa (RFC3), and 40-kDa (RFC2) subunit genes of human replication factor C to chromosome bands 12q24.2-q24.3, 3q27, 13q12.3-q13, and 7q11.23". Genomics. 25 (1): 274–8. doi:10.1016/0888-7543(95)80135-9. PMID 7774928.

[entrez-6] "Entrez Gene: RFC3 replication factor C (activator 1) 3, 38kDa".

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