RFC5

RFC5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1LFS
Identifiers
Aliases	RFC5, RFC36, replication factor C subunit 5
External IDs	OMIM: 600407; MGI: 1919401; HomoloGene: 6730; GeneCards: RFC5; OMA:RFC5 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	118,033,130 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	117,527,112 bp
RNA expression pattern
	Top expressed in
	pons; ; superior vestibular nucleus; ; body of tongue; ; internal globus pallidus; ; Skeletal muscle tissue of biceps brachii; ; endothelial cell; ; inferior ganglion of vagus nerve; ; Brodmann area 23; ; subthalamic nucleus; ; right ventricle;
	Top expressed in
	epiblast; ; embryo; ; bone marrow; ; embryo; ; yolk sac; ; thymus; ; ventricular zone; ; tail of embryo; ; neural tube; ; mesencephalon;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; DNA binding; single-stranded DNA helicase activity; protein binding; ATP binding; enzyme binding; DNA clamp loader activity;
Cellular component	DNA replication factor C complex; Ctf18 RFC-like complex; nucleoplasm; nucleus;
Biological process	nucleotide-excision repair, DNA gap filling; error-free translesion synthesis; error-prone translesion synthesis; positive regulation of DNA-directed DNA polymerase activity; translesion synthesis; transcription-coupled nucleotide-excision repair; nucleotide-excision repair, DNA incision; nucleotide-excision repair, DNA incision, 5'-to lesion; DNA replication; DNA repair; telomere maintenance via semi-conservative replication; DNA-dependent DNA replication; regulation of signal transduction by p53 class mediator;
	Sources:Amigo / QuickGO
Orthologs
	5985
	72151
	ENSG00000111445
	ENSMUSG00000029363
	P40937
	Q9D0F6
NM_001130112; NM_001130113; NM_001206801; NM_007370; NM_181578;
	NM_001346815
	NM_028128
NP_001123584; NP_001123585; NP_001193730; NP_001333744; NP_031396;
	NP_853556
	NP_082404
	Wikidata
View/Edit Human	View/Edit Mouse

Replication factor C subunit 5 is a protein that in humans is encoded by the RFC5 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000111445 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029363 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Okumura K, Nogami M, Taguchi H, Dean FB, Chen M, Pan ZQ, Hurwitz J, Shiratori A, Murakami Y, Ozawa K (Jan 1995). "Assignment of the 36.5-kDa (RFC5), 37-kDa (RFC4), 38-kDa (RFC3), and 40-kDa (RFC2) subunit genes of human replication factor C to chromosome bands 12q24.2-q24.3, 3q27, 13q12.3-q13, and 7q11.23". Genomics. 25 (1): 274–8. doi:10.1016/0888-7543(95)80135-9. PMID 7774928.
^ "Entrez Gene: RFC5 replication factor C (activator 1) 5, 36.5kDa".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000111445 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000029363 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7774928-5] Okumura K, Nogami M, Taguchi H, Dean FB, Chen M, Pan ZQ, Hurwitz J, Shiratori A, Murakami Y, Ozawa K (Jan 1995). "Assignment of the 36.5-kDa (RFC5), 37-kDa (RFC4), 38-kDa (RFC3), and 40-kDa (RFC2) subunit genes of human replication factor C to chromosome bands 12q24.2-q24.3, 3q27, 13q12.3-q13, and 7q11.23". Genomics. 25 (1): 274–8. doi:10.1016/0888-7543(95)80135-9. PMID 7774928.

[entrez-6] "Entrez Gene: RFC5 replication factor C (activator 1) 5, 36.5kDa".

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