RFX6

RFX6
Identifiers
Aliases	RFX6, MTCHRS, MTFS, RFXDC1, dJ955L16.1, regulatory factor X6
External IDs	OMIM: 612659; MGI: 2445208; HomoloGene: 18318; GeneCards: RFX6; OMA:RFX6 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	116,932,161 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	51,606,528 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; testicle; ; gonad; ; duodenum; ; rectum; ; body of pancreas; ; jejunal mucosa; ; pylorus; ; body of stomach; ; mucosa of sigmoid colon;
	Top expressed in
	islet of Langerhans; ; embryo; ; embryo; ; mesenchyme; ; ear; ; endoderm; ; inner ear; ; ectoderm; ; intestine; ; otic vesicle;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor activity;
Cellular component	nucleus; nucleolus;
Biological process	cell differentiation; regulation of transcription, DNA-templated; pancreatic epsilon cell differentiation; glucose homeostasis; regulation of insulin secretion; pancreatic A cell differentiation; transcription, DNA-templated; positive regulation of transcription, DNA-templated; multicellular organism development; positive regulation of insulin secretion involved in cellular response to glucose stimulus; type B pancreatic cell differentiation; pancreatic D cell differentiation; endocrine pancreas development; positive regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	222546
	320995
	ENSG00000185002
	ENSMUSG00000019900
	Q8HWS3
	Q8C7R7
	NM_173560
	NM_001159389; NM_177306
	NP_775831
	NP_001152861; NP_796280
	Wikidata
View/Edit Human	View/Edit Mouse

Regulatory factor X, 6 also known as DNA-binding protein RFX6 is a protein that in humans is encoded by the RFX6 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000185002 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000019900 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Regulatory factor X, 6". Retrieved 2012-02-10.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000185002 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000019900 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Regulatory factor X, 6". Retrieved 2012-02-10.

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