RFamide peptide family

The RFamide peptide family, or the RFamide-related peptides (RFRPs), are a family of neuropeptides.^[1]^[2] They are characterized by the possession of an Arg-Phe-NH₂ motif at their C-terminal extremities.^[1]^[2]

Members of the family include:^[1]^[2]

Neuropeptide FF group
- Neuropeptide AF
- Neuropeptide FF
- Neuropeptide SF (RFRP-1)
- Neuropeptide VF (RFRP-3) (GnIH - avian species)
Prolactin-releasing peptide (PrRP)
Pyroglutamylated RFamide peptide (QRFP)
Kisspeptin (disputed)^[3]

^ ^a ^b ^c Abba Kastin; Abba J. Kastin (28 April 2011). Handbook of Biologically Active Peptides. Academic Press. pp. 779–. ISBN 978-0-08-046379-7.
^ ^a ^b ^c Findeisen, Maria; Rathmann, Daniel; Beck-Sickinger, Annette G. (2011). "RFamide Peptides: Structure, Function, Mechanisms and Pharmaceutical Potential". Pharmaceuticals. 4 (9): 1248–1280. doi:10.3390/ph4091248. ISSN 1424-8247. PMC 4058657.
^ Yun S, Kim DK, Furlong M, Hwang JI, Vaudry H, Seong JY (2014). "Does Kisspeptin Belong to the Proposed RF-Amide Peptide Family?". Front Endocrinol (Lausanne). 5: 134. doi:10.3389/fendo.2014.00134. PMC 4131245. PMID 25165463.

[KastinKastin2011-1] Abba Kastin; Abba J. Kastin (28 April 2011). Handbook of Biologically Active Peptides. Academic Press. pp. 779–. ISBN 978-0-08-046379-7.

[FindeisenRathmann2011-2] Findeisen, Maria; Rathmann, Daniel; Beck-Sickinger, Annette G. (2011). "RFamide Peptides: Structure, Function, Mechanisms and Pharmaceutical Potential". Pharmaceuticals. 4 (9): 1248–1280. doi:10.3390/ph4091248. ISSN 1424-8247. PMC 4058657.

[pmid25165463-3] Yun S, Kim DK, Furlong M, Hwang JI, Vaudry H, Seong JY (2014). "Does Kisspeptin Belong to the Proposed RF-Amide Peptide Family?". Front Endocrinol (Lausanne). 5: 134. doi:10.3389/fendo.2014.00134. PMC 4131245. PMID 25165463.

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