RNA polymerase II

Function of RNA polymerase II (transcription). Green: newly synthesized RNA strand by enzyme

RNA polymerase II (RNAP II and Pol II) is a multiprotein complex that transcribes DNA into precursors of messenger RNA (mRNA) and most small nuclear RNA (snRNA) and microRNA.[1][2] It is one of the three RNAP enzymes found in the nucleus of eukaryotic cells.[3] A 550 kDa complex of 12 subunits, RNAP II is the most studied type of RNA polymerase. A wide range of transcription factors are required for it to bind to upstream gene promoters and begin transcription.

  1. ^ Kornberg RD (December 1999). "Eukaryotic transcriptional control". Trends in Cell Biology. 9 (12): M46–9. doi:10.1016/S0962-8924(99)01679-7. PMID 10611681.
  2. ^ Sims RJ, Mandal SS, Reinberg D (June 2004). "Recent highlights of RNA-polymerase-II-mediated transcription". Current Opinion in Cell Biology. 16 (3): 263–71. doi:10.1016/j.ceb.2004.04.004. PMID 15145350.
  3. ^ Cite error: The named reference :0 was invoked but never defined (see the help page).