RNPEP

RNPEP
Identifiers
Aliases	RNPEP, AP-B, arginyl aminopeptidase, APB
External IDs	OMIM: 602675; MGI: 2384902; HomoloGene: 10628; GeneCards: RNPEP; OMA:RNPEP - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	202,006,147 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	135,211,822 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; duodenum; ; granulocyte; ; rectum; ; monocyte; ; gonad; ; right uterine tube; ; mucosa of esophagus; ; olfactory zone of nasal mucosa; ; stromal cell of endometrium;
	Top expressed in
	granulocyte; ; seminal vesicula; ; crypt of lieberkuhn of small intestine; ; epithelium of stomach; ; jejunum; ; duodenum; ; pyloric antrum; ; molar; ; right kidney; ; genital tubercle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	peptide binding; zinc ion binding; peptidase activity; aminopeptidase activity; metalloexopeptidase activity; metalloaminopeptidase activity; metallopeptidase activity; hydrolase activity; metal ion binding; epoxide hydrolase activity;
Cellular component	plasma membrane; extracellular exosome; secretory granule; extracellular space; extracellular region;
Biological process	proteolysis; negative regulation of blood pressure; peptide catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	6051
	215615
	ENSG00000176393
	ENSMUSG00000041926
	Q9H4A4
	Q8VCT3
	NM_020216; NM_001319182; NM_001319183; NM_001319184
	NM_001159624; NM_145417
	NP_001306111; NP_001306112; NP_001306113; NP_064601
	NP_001153096; NP_663392
	Wikidata
View/Edit Human	View/Edit Mouse

Aminopeptidase B is an enzyme that in humans is encoded by the RNPEP gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000176393 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000041926 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Aurich-Costa J, Cadel S, Gouzy C, Foulon T, Cherif D, Cohen P (Apr 1998). "Assignment of the aminopeptidase B gene (RNPEP) to human chromosome 1 band q32 by in situ hybridization". Cytogenet Cell Genet. 79 (1–2): 143–4. doi:10.1159/000134703. PMID 9533033.
^ Foulon T, Cadel S, Cohen P (Oct 1999). "Aminopeptidase B (EC 3.4.11.6)". Int J Biochem Cell Biol. 31 (7): 747–50. doi:10.1016/S1357-2725(99)00021-7. PMID 10467730.
^ "Entrez Gene: RNPEP arginyl aminopeptidase (aminopeptidase B)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000176393 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000041926 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9533033-5] Aurich-Costa J, Cadel S, Gouzy C, Foulon T, Cherif D, Cohen P (Apr 1998). "Assignment of the aminopeptidase B gene (RNPEP) to human chromosome 1 band q32 by in situ hybridization". Cytogenet Cell Genet. 79 (1–2): 143–4. doi:10.1159/000134703. PMID 9533033.

[pmid10467730-6] Foulon T, Cadel S, Cohen P (Oct 1999). "Aminopeptidase B (EC 3.4.11.6)". Int J Biochem Cell Biol. 31 (7): 747–50. doi:10.1016/S1357-2725(99)00021-7. PMID 10467730.

[entrez-7] "Entrez Gene: RNPEP arginyl aminopeptidase (aminopeptidase B)".

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