ROBO4

ROBO4
Identifiers
Aliases	ROBO4, ECSM4, MRB, roundabout guidance receptor 4, AOVD3
External IDs	OMIM: 607528; MGI: 1921394; HomoloGene: 10397; GeneCards: ROBO4; OMA:ROBO4 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	124,898,500 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	37,326,411 bp
RNA expression pattern
	Top expressed in
	lower lobe of lung; ; apex of heart; ; upper lobe of lung; ; upper lobe of left lung; ; spleen; ; sural nerve; ; subcutaneous adipose tissue; ; right lung; ; visceral pleura; ; endothelial cell;
	Top expressed in
	interventricular septum; ; muscle of thigh; ; left lung; ; right ventricle; ; digastric muscle; ; myocardium of ventricle; ; urethra; ; female urethra; ; left lung lobe; ; extraocular muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	signaling receptor activity; cell-cell adhesion mediator activity;
Cellular component	integral component of membrane; extracellular exosome; plasma membrane; axon;
Biological process	multicellular organism development; cell differentiation; regulation of cell migration; angiogenesis; homophilic cell adhesion via plasma membrane adhesion molecules; axon guidance; dendrite self-avoidance;
	Sources:Amigo / QuickGO
Orthologs
	54538
	74144
	ENSG00000154133
	ENSMUSG00000032125
	Q8WZ75
	Q8C310
	NM_001301088; NM_019055
	NM_028783; NM_001309390
	NP_001288017; NP_061928
	NP_001296319; NP_083059
	Wikidata
View/Edit Human	View/Edit Mouse

Roundabout homolog 4 is a protein that in humans is encoded by the ROBO4 gene.^[5]^[6]