Rabbit hemorrhagic disease

Rabbit hemorrhagic disease virus
CryoEM reconstruction of the virus capsid. EMDB entry EMD-1933[2]
Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Pisuviricota
Class: Pisoniviricetes
Order: Picornavirales
Family: Caliciviridae
Genus: Lagovirus
Species:
Rabbit hemorrhagic disease virus
Isolates[1]
  • RHDV [FRG/89] (RHDV-FRG)
  • RCV [ITL/95] (RHDV-RCV)
  • RCV-A1 [MIC-07/2007/AU] (RHDV-RCV-A1)
  • RHDV [Ashington/1998/UK] (RHDV-Ash)
Synonyms
  • Lagovirus europeus GI
    Pendu et al., 2017[3]
Rabbit Calicivirus CSIRO

Rabbit hemorrhagic disease (RHD), also known as viral hemorrhagic disease (VHD), is a highly infectious and lethal form of viral hepatitis that affects European rabbits. Some viral strains also affect hares and cottontail rabbits. Mortality rates generally range from 70 to 100 percent.[4] The disease is caused by strains of rabbit hemorrhagic disease virus (RHDV), a lagovirus in the family Caliciviridae.

  1. ^ "ICTV 9th Report (2011) Caliciviridae". International Committee on Taxonomy of Viruses (ICTV). Retrieved 9 January 2019.[dead link]
  2. ^ Luque, D; González, JM; Gómez-Blanco, J; et al. (2012). "Epitope Insertion at the N-Terminal Molecular Switch of the Rabbit Hemorrhagic Disease Virus T=3 Capsid Protein Leads to Larger T=4 Capsids". Journal of Virology. 86 (12): 6470–6480. doi:10.1128/JVI.07050-11. PMC 3393579. PMID 22491457.
  3. ^ Le Pendu, J.; et al. (2017). "Proposal for a unified classification system and nomenclature of lagoviruses". The Journal of General Virology. 98 (7): 1658–1666. doi:10.1099/jgv.0.000840. PMID 28714849.
  4. ^ Capucci, L; Cavadini, P; Schiavitto, M; et al. (2017). "Increased pathogenicity in rabbit haemorrhagic disease virus type 2 (RHDV2)". Veterinary Record. 180 (17): 426. doi:10.1136/vr.104132. PMID 28341721.