Radiation proctitis

Radiation proctitis
Other namesRadiation proctopathy, Radiation associated vascular ectasias (RAVE)
Endoscopic image of radiation associated vascular ectasias (RAVE) before and after therapy with argon plasma coagulation.
SpecialtyGastroenterology Edit this on Wikidata
SymptomsPelvic pain, tenesmus, diarrhea, urgency, hematochezia
ComplicationsAnemia, perforation, fistulae
TypesAcute (<3 months after radiation) and Chronic (>3 months after radiation)
CausesPelvic radiation for cancer
Diagnostic methodColonoscopy or flexible sigmoidoscopy
Differential diagnosisInfectious proctitis, inflammatory bowel disease
TreatmentEndoscopy with argon plasma coagulation, bipolar electrocautery, radiofrequency ablation

Radiation proctitis or radiation proctopathy is a condition characterized by damage to the rectum after exposure to x-rays or other ionizing radiation as a part of radiation therapy.[1] Radiation proctopathy may occur as acute inflammation called "acute radiation proctitis" (and the related radiation colitis) or with chronic changes characterized by radiation associated vascular ectasiae (RAVE) and chronic radiation proctopathy.[2][1] Radiation proctitis most commonly occurs after pelvic radiation treatment for cancers such as cervical cancer, prostate cancer, bladder cancer, and rectal cancer. RAVE and chronic radiation proctopathy involves the lower intestine, primarily the sigmoid colon and the rectum, and was previously called chronic radiation proctitis, pelvic radiation disease and radiation enteropathy.[3]

  1. ^ a b Babb RR (1996). "Radiation proctitis: a review". Am. J. Gastroenterol. 91 (7): 1309–11. PMID 8677984.
  2. ^ Mahmood, Sultan; Bollipo, Steven; Steele, Scott; Bristow, Robert G.; Choudhury, Ananya; Oakland, Kathryn; Martin, Jarad (2020-10-20). "It's All the RAVE: Time to Give up on the "Chronic Radiation Proctitis" Misnomer". Gastroenterology. 160 (3): 635–638. doi:10.1053/j.gastro.2020.09.054. ISSN 0016-5085. PMID 33096102.
  3. ^ Cite error: The named reference pmid22858731 was invoked but never defined (see the help page).