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In the long-running British science fiction television series Doctor Who, regeneration is a biological ability exhibited by the Time Lords, a race of fictional humanoids originating on the planet Gallifrey. This process allows a Time Lord to undergo a transformation into a new physical form and a somewhat different personality after instances which would normally result in death. Regeneration has been used multiple times throughout the history of the show as a device for introducing a new actor for the lead role of its main character, the Doctor. Other Time Lords and similar characters have also regenerated, usually for narrative reasons, rather than casting.
Ncuti Gatwa has portrayed the Fifteenth Doctor since "The Giggle" (2023).