Rey is a surname. Notable people with the surname include:
- Abel Rey, French philosopher and historian of science.
- Alain Rey, French linguist, lexicographer and radio personality
- Alain Rey (ski mountaineer), Swiss ski mountaineer
- Alejandro Rey, Argentine actor
- Alexandre Rey (born 1972), Swiss former footballer
- Alvino Rey, American musician
- Ana del Rey, Spanish actor
- André Rey (footballer), French footballer
- André Rey (psychologist), Swiss psychologist
- Anthony Rey, French Jesuit
- Bárbara Rey, Spanish television moderator and actress
- Barret Rey, American college baseball coach
- Blanca del Rey, Spanish flamenco dancer and choreographer
- Dominique Rey, French clergy, bishop of Fréjus-Toulon
- Émile Rey (1846-1895), alpine mountain guide
- Eugene Rey (1838–1909), German chemist and ornithologist
- Fernando Rey, the stage name of Spanish-born actor Fernando Casado D'Arambillet
- Gabriel Venance Rey, French general of the French Revolution and Napoleonic Wars
- Hans Rey, German cyclist
- H. A. Rey and Margret Rey, authors of the Curious George series of children's books
- Jacques Rey (born 1942), French politician
- Jean-Baptiste Rey (1734-1810), French conductor and composer
- Jean Rey (physician), French physician and chemist
- Jean Rey (politician), Belgian Liberal politician, former president of the European Commission
- Jean-Yves Rey, Swiss ski mountaineer
- José Manuel Rey, Venezuelan football player
- Julio Rey, Spanish marathon runner
- Lana Del Rey, American singer, songwriter, record producer, and model
- Louis-Charles-Joseph Rey (1738–1811), cellist and composer
- Louis Emmanuel Rey, French general of the French Revolution and Napoleonic Wars
- Luis Rey, Spanish-Mexican artist and Led Zeppelin expert
- Nicholas Andrew Rey, United States ambassador
- Micheline Calmy-Rey, Swiss politician
- Ofelia Rey Castelao, Spanish historian, writer, and university professor
- Paola Rey, Colombian actress
- Reynaldo Rey, American actor and comedian
- Robert Rey, plastic surgeon and subject of Dr. 90210 reality television show
- Tony Rey (musician), American guitarist
- Willy Rey, Playboy Playmate of the Month, February 1971