Risedronic acid

Risedronic acid
Clinical data
Trade namesActonel, Atelvia, Benet, others
AHFS/Drugs.comMonograph
License data
Pregnancy
category
  • AU: B3
Routes of
administration		By mouth
ATC code
Legal status
Legal status
  • AU: S4 (Prescription only)
  • UK: POM (Prescription only)
  • US: ℞-only[1]
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability0.63%
Protein binding~24%
MetabolismNone
Elimination half-life1.5 h
ExcretionKidney and fecal
Identifiers
  • (1-hydroxy-1-phosphono-2-pyridin-3-yl-ethyl)phosphonic acid
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
PDB ligand
CompTox Dashboard (EPA)
ECHA InfoCard100.116.436 Edit this at Wikidata
Chemical and physical data
FormulaC7H11NO7P2
Molar mass283.113 g·mol−1
3D model (JSmol)
  • OC(Cc1cccnc1)(P(=O)(O)O)P(=O)(O)O
  • InChI=1S/C7H11NO7P2/c9-7(16(10,11)12,17(13,14)15)4-6-2-1-3-8-5-6/h1-3,5,9H,4H2,(H2,10,11,12)(H2,13,14,15) ☒N
  • Key:IIDJRNMFWXDHID-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Risedronic acid, often used as its sodium salt risedronate sodium, is a bisphosphonate.[1] It slows down the cells which break down bone.[1] It's used to treat or prevent osteoporosis, and treat Paget's disease of bone.[1] It is taken by mouth.[1]

It was patented in 1984 and approved for medical use in 1998.[2]

  1. ^ a b c d e "Actonel- risedronate sodium tablet, film coated". DailyMed. 1 November 2019. Retrieved 28 June 2022.
  2. ^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 523. ISBN 9783527607495.