The Roman Catholic Archdiocese of Mbandaka-Bikoro (Latin: Mbandakan(us)–Bikoroën(sis)) is the Metropolitan See for the Latin Rite Ecclesiastical province of Mbandaka-Bikoro, in the western part of Democratic Republic of the Congo. It is under the authority of the Congregation for the Evangelization of Peoples.
The cathedral archiepiscopal see is at the Cathedral of St. Eugene, in Mbandaka, Équateur Province.