Romantic epistemology emerged from the Romantic challenge to both the static, materialist views of the Enlightenment (Hobbes) and the contrary idealist stream (Hume) when it came to studying life. Romanticism needed to develop a new theory of knowledge that went beyond the method of inertial science, derived from the study of inert nature (natura naturata), to encompass vital nature (natura naturans). Samuel Taylor Coleridge was at the core of the development of the new approach, both in terms of art and the 'science of knowledge' itself (epistemology). Coleridge's ideas regarding the philosophy of science involved Romantic science in general, but Romantic medicine in particular, as it was essentially a philosophy of the science(s) of life.