Rostam Khan (fl. second half of the 17th century) was a Safavid military commander, gholam, and official from the Georgian Saakadze family. He served as commander-in-chief (sepahsalar-e Iran), commander of the musketeer corps (tofangchi-aghasi), chancellor/chief justice (divanbegi), and governor (beglarbeg) of the Azerbaijan Province under king (shah) Suleiman I (r. 1666-1694).
Rostam Khan was a son of Safiqoli Khan, and a namesake to his prominent grandfather, who also held the position of commander-in-chief and beglarbeg of Azerbaijan.
According to Italian traveller Gemelli Careri, when Rostam Khan's nephew Bijan Beg fell out of favor during Shaykh Ali Khan Zanganeh's vizierate, he was saved through Rostam Khan's intervention.