Rupatadine

Rupatadine

Clinical data
Trade names	Rupafin, others
AHFS/Drugs.com	International Drug Names
Routes of administration	By mouth
ATC code	R06AX28 (WHO)
Legal status
Legal status	CA: ℞-only[1] EU: Rx-only[2] In general: ℞ (Prescription only)
Pharmacokinetic data
Protein binding	98–99%
Metabolism	Liver, CYP-mediated
Elimination half-life	5.9 hours
Excretion	34.6% urine, 60.9% faeces
Identifiers
IUPAC name 8-Chloro-6,11-dihydro-11-[1-[(5-methyl-3-pyridinyl)methyl]-4-piperidinylidene]-5H-benzo[5,6]cyclohepta[1,2-b]pyridine fumarate
CAS Number	158876-82-5 N (free base) 182349-12-8 (fumarate)
PubChem CID	133017
DrugBank	DB11614 N
ChemSpider	117388 Y
UNII	2AE8M83G3E
KEGG	D07407 N
ChEBI	CHEBI:135673
ChEMBL	ChEMBL91397 Y
CompTox Dashboard (EPA)	DTXSID00166534
ECHA InfoCard	100.260.389
Chemical and physical data
Formula	C26H26ClN3
Molar mass	415.97 g·mol−1
3D model (JSmol)	Interactive image
SMILES Clc1cc5c(cc1)\C(=C3/CCN(Cc2cncc(c2)C)CC3)c4ncccc4CC5
InChI InChI=1S/C26H26ClN3/c1-18-13-19(16-28-15-18)17-30-11-8-20(9-12-30)25-24-7-6-23(27)14-22(24)5-4-21-3-2-10-29-26(21)25/h2-3,6-7,10,13-16H,4-5,8-9,11-12,17H2,1H3 Y Key:WUZYKBABMWJHDL-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Rupatadine is a second generation antihistamine and platelet-activating factor antagonist used to treat allergies. It was discovered and developed by Uriach [es]^[3] and is marketed as Rupafin and under several other trade names.