S1PR4

S1PR4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2DCO
Identifiers
Aliases	S1PR4, EDG6, LPC1, S1P4, SLP4, sphingosine-1-phosphate receptor 4
External IDs	OMIM: 603751; MGI: 1333809; HomoloGene: 2799; GeneCards: S1PR4; OMA:S1PR4 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	3,180,332 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	81,335,966 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; blood; ; monocyte; ; spleen; ; bone marrow; ; trabecular bone; ; bone marrow cells; ; lymph node; ; upper lobe of left lung; ; right lung;
	Top expressed in
	granulocyte; ; blood; ; tibiofemoral joint; ; mesenteric lymph nodes; ; spleen; ; bone marrow; ; thymus; ; right lung; ; right lung lobe; ; subcutaneous adipose tissue;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	sphingosine-1-phosphate receptor activity; G protein-coupled receptor activity; signal transducer activity; lipid binding;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane; mitochondrion;
Biological process	positive regulation of cytosolic calcium ion concentration; G protein-coupled receptor signaling pathway; adenylate cyclase-activating G protein-coupled receptor signaling pathway; activation of phospholipase C activity; immune response; sphingosine-1-phosphate receptor signaling pathway; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	8698
	13611
	ENSG00000125910
	ENSMUSG00000044199
	O95977
	Q9Z0L1
	NM_003775
	NM_010102
	NP_003766
	NP_034232
	Wikidata
View/Edit Human	View/Edit Mouse

Sphingosine-1-phosphate receptor 4 also known as S1PR4 is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P). Hence this receptor is also known as S1P₄.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000125910 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000044199 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: S1PR4 Sphingosine-1-phosphate receptor 4".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000125910 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000044199 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: S1PR4 Sphingosine-1-phosphate receptor 4".

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